Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A.
نویسندگان
چکیده
An effective theranostic platform based on porous silica nanoparticles encapsulated with the complex of a photodynamic anticancer drug and graphene quantum dots (GQDs), with the bifunction of multicolor imaging and satisfactory photo-induced anticancer activity, was successfully designed and prepared for in vitro photodynamic therapy (PDT) of superficial cancer.
منابع مشابه
Fluorescent Contrast agent Based on Graphene Quantum Dots Decorated Mesoporous Silica Nanoparticles for Detecting and Sorting Cancer Cells
Background and Objectives: The inability of classic fluorescence-activated cell sorting to single cancer cell sorting is one of the most significant drawbacks of this method. The sorting of cancer cells in microdroplets significantly influences our ability to analyze cancer cell proteins. Material and Methods: We adapted a developed microfluidic device as a 3D in vitro model to sorted MCF-7 c...
متن کاملGraphene Quantum Dots-Coated Bismuth Nanoparticles for X-ray CT Imaging-Guided Photothermal therapy of Cancer Cells
Introduction: Theranostic nanoparticles, which integrate both diagnostic and therapeutic capabilities into one nanoagent, has great promise to ablate more effective tumoral tissue by optimizing and real-time monitoring treatment interventions, as well as monitoring therapeutic response to corresponding effect. Multifunctional theranostic nanoagent based on graphene quantum dots...
متن کاملComparative Studies of High Contrast Fluorescence Imaging Efficiency of Silica-coated CdSe Quantum Dots with Green and Red Emission
Herein we report the possibility of using green and red emitting silica-coated cadmium selenide (CdSe) quantum dots (QDs) for remarkable stem and cancer cellular imaging, efficient cellular uptake and fluorescence imaging of semi and ultra-thin sections of tumor for in vivo tumor targeted imaging applications. The comparative studies of high contrast cellular imaging behaviours of the silica-co...
متن کاملThe effect of doping Graphene Quantum Dots with K, B, N, and Cl on its emitted spectrum
In this work, the effect of doping Graphene Quantum Dots (GQDs) on their emission spectra has been studied. First, graphene has been deposited on SiC substrate by using sublimation method. Second, doped-GQDs have been distributed on the surface of graphene via drop casting. The structure of the samples have been studied and characterized by X-ray diffraction (XRD), Scanning Electron Microscopy ...
متن کاملA Sensitive Sensor for Nano-Molar Detection of 5-Fluorouracil by Modifying a Paste Sensor with Graphene Quantum Dots and an Ionic Liquid
5-fluorouracil is a widely used anticancer drug with many side effects on humans, and hence its analysis in biological samples is very important. Accordingly, a novel sensitive electrochemical approach was fabricated by incorporating graphene quantum dots (GCD) and 1-butylpyridinium bromide (BPBr) in the formulation of a carbon paste electrode (GQD/BPBr/CPE). The GQD was synthesized and charact...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 51 2 شماره
صفحات -
تاریخ انتشار 2015